Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10549243 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL10546758 | 0.84 | RIPK1 (0.51) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL10549648 | 0.80 | PDK1 (0.45) | ALDH1A1LMNAKMT2AMEN1RAB9A | |
| SCHEMBL10546564 | 0.76 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL10547048 | 0.75 | TP53 (0.48) | ALDH1A1LMNAHPGDSMN1; SMN2RAB9A | |
| SCHEMBL22971541 | 0.75 | MEN1 (0.49) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL10548744 | 0.72 | MLYCD (0.48) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10546095 | 0.71 | KMT2A (0.44) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10548973 | 0.71 | RIPK1 (0.53) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL28958770 | 0.69 | HSP90AA1 (0.58) | ALDH1A1LMNAHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814341-A | HISTAMINE H2 ANTAGONISTS | REITER LAWRENCE A (US) | 1989-03-21 | — | — | US | disclosed |