SCHEMBL10568357

SCHEMBL10568357

CC(C)O[SiH2]Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
CA4 P22748 1/20 0.39
LTA4H P09960 2/20 0.36
TSHR P16473 1/20 0.36
PTGS1 P23219 2/20 0.34
MAOA P21397 1/20 0.34
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
GAA P10253 1/20 0.32
KDM4E B2RXH2 1/20 0.32
KCNA3 P22001 1/20 0.31
MTNR1A P48039 3/20 0.31
MTNR1B P49286 3/20 0.31
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
CYP2D6 P10635 1/20 0.31
ADRB3 P13945 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23457306 0.88 ALDH1A3 (0.32) KMT2A
SCHEMBL28938941 0.81 CA4 (0.39) LMNACA4LTA4HTSHRPTGS1
SCHEMBL707758 0.77 LTA4H (0.50) LMNACA4LTA4HTSHRMAOA
Biphenyl SCHEMBL1228336 0.76 ALDH1A1 (0.45) LMNAMAOAALDH1A1L3MBTL1GAA
SCHEMBL28647571 0.76 IDO1 (0.35) LMNALTA4HTSHRKDM4ECYP2D6
Hydrochloric Acid SCHEMBL9709369 0.75 LTA4H (0.47) LMNACA4LTA4HTSHRMAOA
SCHEMBL2115587 0.73 CA4 (0.50) LMNACA4LTA4HTSHRMAOA
SCHEMBL9715684 0.72 LTA4H (0.45) LMNACA4LTA4HTSHRMAOA
Butane SCHEMBL2501351 0.71 LTA4H (0.43) LMNACA4LTA4HTSHRL3MBTL1
SCHEMBL705070 0.71 CA4 (0.42) LMNACA4LTA4HTSHRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715680-B Process for preparing high cis-1, 4-polydienes with lanthanide-based catalyst compositions 株式会社普利司通 2021-10-19 CN disclosed
CN-111433257-A Polysiloxane, composition containing same, and cured film using same 默克专利有限公司 2020-07-17 CN disclosed
US-4831091-A USING A COORDINATION CATALYST CONTAINING A SILANETRIOL OR -DIOL AS WELL AS AN AROMATIC ESTSER; ODORLESS; STEREOSPECIFIC; PARTICLE SIZES CHISSO CORPORATION (JP) 1989-05-16 US disclosed