Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574269 | 0.92 | NPC1 (0.48) | SLC2A1NPC1SMN1; SMN2RAB9ATRPV1 | |
| SCHEMBL10574680 | 0.88 | NPBWR1 (0.59) | NPC1SMN1; SMN2RAB9ATRPV1MEN1 | |
| SCHEMBL10576087 | 0.88 | ALOX5 (0.56) | TRPV1ALDH1A1HPGDCHEK2KDM4E | |
| SCHEMBL10578710 | 0.87 | MEN1 (0.49) | NPC1SMN1; SMN2RAB9ATRPV1MEN1 | |
| SCHEMBL10577338 | 0.87 | DGAT1 (0.57) | SMN1; SMN2TRPV1MAPTNPBWR1TP53 | |
| SCHEMBL10578004 | 0.87 | NPBWR1 (0.58) | TRPV1NPBWR1 | |
| SCHEMBL10578455 | 0.87 | NPBWR1 (0.56) | NPC1SMN1; SMN2RAB9ATRPV1MEN1 | |
| SCHEMBL10574094 | 0.86 | DGAT1 (0.44) | SLC2A1TRPV1MAPTNPBWR1ALDH1A1 | |
| SCHEMBL10574710 | 0.86 | NPC1 (0.51) | NPC1SMN1; SMN2RAB9ATRPV1GAA | |
| SCHEMBL10573294 | 0.85 | TCF4 (0.53) | SMN1; SMN2TRPV1MAPTNPBWR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |