Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 19/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020728 | 0.90 | AMY1A (0.48) | AMY1ACHEK2 | |
| SCHEMBL11019903 | 0.89 | AMY1A (0.47) | AMY1A | |
| SCHEMBL11020368 | 0.87 | AMY1A (0.46) | AMY1A | |
| SCHEMBL11017268 | 0.87 | CHEK2 (0.47) | AMY1ACHEK2 | |
| SCHEMBL11016456 | 0.87 | CHEK2 (0.44) | AMY1ACHEK2 | |
| SCHEMBL11018142 | 0.84 | AMY1A (0.43) | AMY1A | |
| SCHEMBL11016884 | 0.84 | CHEK2 (0.41) | AMY1ACHEK2 | |
| SCHEMBL11019266 | 0.83 | AMY1A (0.43) | AMY1A | |
| SCHEMBL11019293 | 0.77 | AMY1A (0.49) | AMY1ACHEK2 | |
| SCHEMBL11019017 | 0.77 | HPSE (0.42) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |