Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | DBH | P09172 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121174 | 0.87 | KDM4E (0.62) | KDM4EDBHGAARECQLGSK3B | |
| SCHEMBL727222 | 0.81 | CES2 (0.54) | KDM4EDBHGAARECQLGSK3B | |
| SCHEMBL508009 | 0.80 | CES2 (0.52) | KDM4EDBHGAARECQLGSK3B | |
| SCHEMBL10941943 | 0.80 | KDM4E (0.56) | KDM4EDBHGAARECQLELANE | |
| SCHEMBL12418688 | 0.80 | KDM4E (0.56) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL480603 | 0.79 | KMT2A (0.58) | KDM4EDBHGAARECQLELANE | |
| SCHEMBL3685675 | 0.79 | KDM4E (0.50) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL688186 | 0.79 | TP53 (0.47) | GAAALDH1A1HDAC6CES2CES1 | |
| SCHEMBL1878288 | 0.78 | TSHR (0.60) | KDM4EDBHGAARECQLALDH1A1 | |
| SCHEMBL585256 | 0.78 | ALDH1A1 (0.56) | KDM4EDBHGAARECQLGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319316-A2 | Griseolic acid monoesters, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |