Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242474 | 0.78 | TSHR (0.40) | TP53TSHRHPGD | |
| SCHEMBL14889733 | 0.78 | LTA4H (0.32) | TSHR | |
| SCHEMBL1355032 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL4955872 | 0.77 | ALDH1A1 (0.40) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8847061 | 0.75 | MGLL (0.42) | — | |
| SCHEMBL10633819 | 0.75 | CYP3A4 (0.35) | ALDH1A1CYP3A4SMN1; SMN2ALOX15MAPT | |
| SCHEMBL10345289 | 0.73 | ACACB (0.36) | — | |
| SCHEMBL10633809 | 0.73 | GABRA1 (0.38) | ALDH1A1KDM4EKMT2AGABRA1AKR1B1 | |
| SCHEMBL9502745 | 0.73 | THRA (0.41) | ALDH1A1CYP3A4SMN1; SMN2TP53KDM4E | |
| SCHEMBL5922911 | 0.72 | ALDH1A1 (0.37) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319472-A2 | Epoxy siloxanes | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |