Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 5/20 | 0.57 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867944 | 0.91 | VCAM1 (0.69) | VCAM1MAPK1GPR35ALDH1A1HPGD | |
| Arsenic SCHEMBL28025098 | 0.90 | VCAM1 (0.68) | VCAM1MAPK1GPR35ALDH1A1HPGD | |
| Methane SCHEMBL27604929 | 0.90 | VCAM1 (0.68) | VCAM1MAPK1GPR35ALDH1A1HPGD | |
| SCHEMBL10037252 | 0.90 | TTR (0.73) | VCAM1MAPK1GPR35ALDH1A1HPGD | |
| Methane SCHEMBL28199058 | 0.90 | VCAM1 (0.68) | VCAM1MAPK1GPR35ALDH1A1HPGD | |
| SCHEMBL29634883 | 0.90 | TTR (0.73) | VCAM1MAPK1GPR35ALDH1A1HPGD | |
| SCHEMBL2156599 | 0.88 | MAPK1 (0.60) | VCAM1MAPK1GPR35ALDH1A1HPGD | |
| SCHEMBL106249 | 0.86 | CASP6 (0.72) | MAPK1GPR35ALDH1A1HPGDTP53 | |
| SCHEMBL2636747 | 0.86 | CASP6 (0.72) | MAPK1GPR35ALDH1A1HPGDTP53 | |
| SCHEMBL27602539 | 0.86 | VCAM1 (0.62) | VCAM1MAPK1GPR35ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216851-C | Process for producing bis (4-hydroxy-3-nitrophenyl) compound | NIPPON KAYAKU KK (JP) | 2005-08-31 | — | — | CN | disclosed |
| US-6608233-B2 | Nitrating a bis(4-hydroxyphenyl) bonded to each other or through an electron-donating bridging group, sulfoxide, sulfone or carbonyl group using nitric acid in a solvent and free from other acids | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2003-08-19 | — | — | US | disclosed |
| CN-1426390-A | Process for producing bis (4-hydroxy-3-nitrophenyl) compound | NIPPON KAYAKU KK (JP) | 2003-06-25 | — | — | CN | disclosed |
| US-20030055288-A1 | Process for producting bis(4-hydroxy-3-nitrophenyl) compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1277727-A1 | PROCESS FOR PRODUCING BIS(4-HYDROXY-3-NITROPHENYL) COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-5977413-A | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0895985-A2 | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | Nippon Kayaku Kabushiki Kaisha (JP) | 1999-02-10 | — | — | EP | disclosed |
| US-3862936-A | Mannich derivatives of 4,4{40 -dihydroxy-3,3{40 dinitrobenzophenone | GESCHICKTER FUND MED RES | 1975-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055288-A1 | Process for producting bis(4-hydroxy-3-nitrophenyl) compound | NOS3, NOS2, NOS1 | VCAM1 3145/4885MAPK1 2163/4885GPR35 3425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.