Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.42 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.40 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.40 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.40 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643826 | 0.81 | CA5A (0.40) | ALDH1A1MAPTPKML3MBTL1KMT2A | |
| SCHEMBL10639487 | 0.80 | MEN1 (0.59) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL27604275 | 0.80 | KCNMA1 (0.50) | ALDH1A1MAPTMEN1KMT2ATAAR1 | |
| SCHEMBL1371186 | 0.75 | KDM4E (0.54) | ALDH1A1MAPTMEN1KMT2AGRM2 | |
| SCHEMBL1491068 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MAPTPKML3MBTL1MEN1 | |
| SCHEMBL16832792 | 0.74 | GAA (0.68) | ALDH1A1MAPTPKML3MBTL1MEN1 | |
| SCHEMBL10643153 | 0.72 | SLC2A1 (0.57) | MAPTPKMRAB9AGRM2 | |
| SCHEMBL24015811 | 0.71 | PKM (0.51) | ALDH1A1MAPTPKML3MBTL1MEN1 | |
| SCHEMBL10644152 | 0.71 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL18321157 | 0.71 | GRM2 (0.49) | ALDH1A1MAPTPKML3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288431-A1 | 3H-1,2,3-triazolo[4,5-d]pyrimidines | CIBA-GEIGY AG (CH) | 1988-10-26 | — | — | EP | disclosed |