Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646741 | 0.93 | DHODH (0.43) | NPC1GMNNLMNATP53CYP1A2 | |
| SCHEMBL10648551 | 0.89 | SMN1; SMN2 (0.44) | NPC1GMNNLMNATP53CYP1A2 | |
| SCHEMBL9812333 | 0.81 | RAB9A (0.65) | NPC1GMNNLMNATP53CYP1A2 | |
| SCHEMBL7783570 | 0.80 | DHODH (0.63) | NPC1GMNNLMNATP53CYP1A2 | |
| SCHEMBL6932048 | 0.77 | MAPT (0.46) | NPC1GMNNLMNATP53CYP1A2 | |
| SCHEMBL6931877 | 0.76 | THRB (0.48) | NPC1GMNNLMNATP53CYP1A2 | |
| SCHEMBL8822110 | 0.76 | ALDH1A1 (0.51) | NPC1HTTRAB9ABLMSMN1; SMN2 | |
| SCHEMBL6937152 | 0.76 | CA1 (0.40) | NPC1GMNNLMNATP53CYP1A2 | |
| SCHEMBL6936296 | 0.76 | RAB9A (0.39) | NPC1GMNNLMNATP53CYP1A2 | |
| SCHEMBL9812325 | 0.74 | RAB9A (0.67) | NPC1GMNNLMNATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257882-A1 | N-Phenyl butenamides with pharmaceutical properties | LILLY INDUSTRIES LIMITED (GB) | 1988-03-02 | — | — | EP | disclosed |