Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646209 | 0.86 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10646149 | 0.70 | KDM4E (0.45) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10645428 | 0.68 | KDM4E (0.41) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5526686 | 0.57 | NPSR1 (0.46) | ALDH1A1NPSR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12138081 | 0.56 | CYP3A4 (0.43) | L3MBTL1ALDH1A1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL5793157 | 0.54 | POLB (0.54) | ALDH1A1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL17014725 | 0.54 | RAB9A (1.00) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2167113 | 0.54 | LMNA (0.54) | L3MBTL1ALDH1A1POLBSMN1; SMN2AR | |
| SCHEMBL7324699 | 0.53 | ABCB1 (0.49) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL974759 | 0.53 | ALDH1A1 (0.69) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121341-B1 | TRIAZOLO(4,3-C)PYRIMIDINES AND TRIAZOLO(1,5-C)PYRIMIDINES SUBSTITUTED BY NITROGEN-CONTAINING HETEROCYCLIC RINGS | RIKER LABORATORIES, INCORPORATED (US) | 1988-11-17 | — | — | EP | claimed |
| US-4477450-A | BRONCHODILATORS | RIKER LABORATORIES, INC. (US) | 1984-10-16 | — | — | US | claimed |
| EP-0121341-A1 | Triazolo(4,3-c)pyrimidines and triazolo(1,5-c)pyrimidines substituted by nitrogen-containing heterocyclic rings | RIKER LABORATORIES, INCORPORATED (US) | 1984-10-10 | — | — | EP | claimed |
| EP-0121341-B1 | TRIAZOLO(4,3-C)PYRIMIDINES AND TRIAZOLO(1,5-C)PYRIMIDINES SUBSTITUTED BY NITROGEN-CONTAINING HETEROCYCLIC RINGS | RIKER LABORATORIES, INCORPORATED (US) | 1988-11-17 | — | — | EP | disclosed |
| US-4536579-A | BRONCHODILATING AGENTS | RIKER LABORATORIES, INC. (US) | 1985-08-20 | — | — | US | disclosed |
| US-4477450-A | BRONCHODILATORS | RIKER LABORATORIES, INC. (US) | 1984-10-16 | — | — | US | disclosed |
| EP-0121341-A1 | Triazolo(4,3-c)pyrimidines and triazolo(1,5-c)pyrimidines substituted by nitrogen-containing heterocyclic rings | RIKER LABORATORIES, INCORPORATED (US) | 1984-10-10 | — | — | EP | disclosed |