Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319929 | 0.83 | TYR (0.50) | TYRMMP1MMP2MMP3MMP7 | |
| SCHEMBL5335059 | 0.77 | GAA (0.52) | MMP1MMP2MMP9MMP13ALDH1A1 | |
| SCHEMBL7758469 | 0.75 | TSHR (0.52) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL32038 | 0.75 | MMP2 (0.55) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL9646612 | 0.75 | MMP13 (0.34) | MMP1MMP2MMP13ALDH1A1HTR2A | |
| SCHEMBL3328706 | 0.74 | TSHR (0.48) | MMP1MMP2MMP9MMP13TDP1 | |
| SCHEMBL11014092 | 0.72 | SMN1; SMN2 (0.47) | TYRMMP1MMP2MMP3MMP7 | |
| SCHEMBL607349 | 0.72 | ENPP2 (0.52) | TYRCYP2A6ALDH1A1CYP2A13 | |
| SCHEMBL226161 | 0.72 | TDP1 (0.64) | TYRMMP1MMP2MMP3MMP7 | |
| SCHEMBL7297885 | 0.71 | HPGD (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757135-A | Copper-containing fiber reactive dye | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| US-3956395-A | Distyrylbenzene disulfone derivatives | MEYER HANS RUDOLF | 1976-05-11 | — | — | US | disclosed |