Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 3/20 | 0.34 |
| ▸ | GABRD | O14764 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.34 |
| ▸ | GABRE | P78334 | 3/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655064 | 0.87 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL10653000 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL10654499 | 0.77 | RECQL (0.36) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL10654409 | 0.74 | PABPC1 (0.42) | ALDH1A1KDM4EHPGDLMNATDP1 | |
| SCHEMBL10655784 | 0.72 | PABPC1 (0.38) | ALDH1A1KDM4EHPGDLMNATDP1 | |
| SCHEMBL10654625 | 0.71 | MEN1 (0.42) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL10653805 | 0.70 | PABPC1 (0.43) | ALDH1A1KDM4EHPGDLMNAPABPC1 | |
| SCHEMBL10654954 | 0.68 | KDM4E (0.47) | ALDH1A1KDM4EHPGDLMNAGABRP | |
| SCHEMBL10918652 | 0.67 | PABPC1 (0.41) | ALDH1A1KDM4EHPGDPABPC1GABRP | |
| SCHEMBL10916358 | 0.66 | PABPC1 (0.37) | ALDH1A1KDM4EHPGDLMNAPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092380-B1 | ANTIALLERGIC 4H-FURO(3,2-B)INDOLES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
| EP-0092380-A2 | Antiallergic 4H-furo(3,2-b)indoles and their production | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | claimed |