Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30450513 | 0.75 | IDH1 (0.51) | MAOBACHEL3MBTL1MAPTMAPK1 | |
| SCHEMBL4516193 | 0.73 | MAOB (0.58) | MAOBACHEL3MBTL1MAPTTDP1 | |
| SCHEMBL988885 | 0.72 | NPC1 (0.55) | MAOBL3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL15910022 | 0.72 | LMNA (0.61) | MAOBACHEL3MBTL1MAPTTDP1 | |
| SCHEMBL9007487 | 0.72 | MAPT (0.80) | L3MBTL1MAPTMAPK1TDP1EDNRA | |
| SCHEMBL5838451 | 0.71 | MEN1 (0.63) | L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL10659236 | 0.71 | RXRA (0.52) | L3MBTL1MAPTMAPK1TDP1EDNRA | |
| SCHEMBL18678480 | 0.71 | L3MBTL1 (0.56) | MAOBACHEL3MBTL1MAPTMAPK1 | |
| SCHEMBL5483956 | 0.71 | MAOB (0.56) | MAOBACHEL3MBTL1MAPTMAPK1 | |
| SCHEMBL7432074 | 0.71 | ACHE (1.00) | MAOBACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |