Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665909 | 0.79 | KDM4E (0.49) | L3MBTL1MEN1KMT2ALMNATSHR | |
| SCHEMBL10665747 | 0.78 | SMN1; SMN2 (0.47) | MEN1KMT2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL27891187 | 0.78 | FFAR2 (0.62) | MEN1KMT2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL10568923 | 0.74 | KCNMA1 (0.48) | MEN1KMT2ALMNASMN1; SMN2RAB9A | |
| SCHEMBL10731537 | 0.73 | HTT (0.42) | L3MBTL1MEN1KMT2ALMNATSHR | |
| SCHEMBL10737795 | 0.72 | MEN1 (0.42) | L3MBTL1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10730705 | 0.71 | HSPA5 (0.43) | L3MBTL1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL10660799 | 0.71 | HSPA5 (0.43) | L3MBTL1MEN1KMT2AHPGDHTT | |
| SCHEMBL1341840 | 0.70 | RAB9A (0.53) | MEN1KMT2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL1340534 | 0.70 | EPHX2 (0.55) | L3MBTL1MEN1KMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736033-A | Certain 1,3-dihydro-1-[heterocyclic)imino]-furo-[3,4-b]quinoline 9-ol compounds having analgesic and anti-inflammatory activity | ROUSSEL UCLAF (FR) | 1988-04-05 | — | — | US | disclosed |
| US-4596875-A | Reacting benzoxazole compound with amide to decyclize, cyclizing to form quinoline derivative | ROUSSEL UCLAF (FR) | 1986-06-24 | — | — | US | disclosed |
| US-4486438-A | 4-Hydroxy-3-quinoline-carboxylic acid derivatives | ROUSSEL UCLAF (FR) | 1984-12-04 | — | — | US | disclosed |