Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568933 | 0.82 | KCNMA1 (0.46) | KCNMA1GAAFFAR2LMNAGCK | |
| SCHEMBL5950450 | 0.74 | KCNMA1 (0.58) | KCNMA1FFAR2LMNAGCKALDH1A1 | |
| SCHEMBL10665897 | 0.74 | L3MBTL1 (0.48) | GAAFFAR2LMNAALDH1A1MEN1 | |
| SCHEMBL10568929 | 0.72 | FFAR2 (0.51) | KCNMA1GAAFFAR2LMNAALDH1A1 | |
| SCHEMBL9601530 | 0.70 | ALDH1A1 (0.43) | GAALMNAALDH1A1MEN1KMT2A | |
| SCHEMBL28353263 | 0.67 | LMNA (0.66) | KCNMA1FFAR2LMNAALDH1A1MEN1 | |
| SCHEMBL30765198 | 0.67 | LMNA (0.66) | KCNMA1FFAR2LMNAALDH1A1MEN1 | |
| SCHEMBL9605058 | 0.66 | KCNMA1 (0.48) | KCNMA1FFAR2LMNAGCKALDH1A1 | |
| SCHEMBL10660799 | 0.65 | HSPA5 (0.43) | FFAR2MEN1KMT2APKMMAPK1 | |
| SCHEMBL5342550 | 0.65 | RAB9A (0.61) | GAALMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845105-A | 4-OH-quinoline carboxylic acid amides having analgesic and anti-inflammatory activity | ROUSSEL UCLAF (FR) | 1989-07-04 | — | — | US | disclosed |