Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6-Chloroguanine SCHEMBL10674719 | 0.88 | LMNA (0.40) | LMNATP53CYP1A2KDM4EGMNN | |
| Ribose (Furanose) SCHEMBL2505730 | 0.83 | ADK (0.40) | LMNATP53CYP1A2KDM4EGMNN | |
| Ribose (Furanose) SCHEMBL4542668 | 0.83 | ADK (0.40) | LMNATP53CYP1A2KDM4EGMNN | |
| SCHEMBL9657336 | 0.81 | LMNA (0.44) | LMNATP53CYP1A2KDM4EGMNN | |
| 2,6-Diaminopurine SCHEMBL8153506 | 0.77 | HIF1A (0.42) | LMNATP53GMNNBLMPMP22 | |
| 2,6-Diaminopurine SCHEMBL10774599 | 0.77 | HIF1A (0.42) | LMNATP53GMNNBLMPMP22 | |
| SCHEMBL37383 | 0.77 | XDH (0.38) | TP53KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL29354230 | 0.77 | XDH (0.38) | TP53KDM4ESMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4763242 | 0.75 | XDH (0.37) | KDM4EHPGD | |
| SCHEMBL11456966 | 0.75 | XDH (0.37) | KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501708-B2 | Adenosine compounds and their use thereof | INOTEK PHARMACEUTICALS CORPORATION (US) | 2013-08-06 | — | — | US | disclosed |
| US-20110245194-A1 | ADENOSINE COMPOUNDS AND THEIR USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245194-A1 | ADENOSINE COMPOUNDS AND THEIR USE THEREOF | ADORA1, ADORA2A, ADORA3 | LMNA 2759/4885TP53 3916/4885CYP1A2 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.