Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676916 | 0.83 | ALDH1A1 (0.46) | RAB9ANPC1ALDH1A1GAAMAPT | |
| SCHEMBL10680630 | 0.81 | NPC1 (0.34) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL10684372 | 0.77 | MAPT (0.34) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL10683554 | 0.76 | UCHL1 (0.43) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL10679912 | 0.75 | CDC7 (0.40) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL7380127 | 0.74 | PDE3B (0.46) | ALDH1A1GAAKDM4EMAPTMEN1 | |
| SCHEMBL10676997 | 0.73 | ALDH1A1 (0.53) | RAB9ANPC1ALDH1A1GAAKDM4E | |
| SCHEMBL10809119 | 0.72 | HSD17B10 (0.39) | NPC1GAAMAPTMEN1KMT2A | |
| SCHEMBL9631567 | 0.70 | TSHR (0.50) | NPC1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10682419 | 0.70 | LMNA (0.39) | RAB9ANPC1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |