Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686306 | 0.85 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BESR1PGR | |
| SCHEMBL10685213 | 0.83 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BESR1PGR | |
| SCHEMBL10690528 | 0.83 | SIGMAR1 (0.56) | ADRA1DADRA1AADRA1BESR1PGR | |
| SCHEMBL10686642 | 0.82 | SIGMAR1 (0.55) | ADRA1DADRA1AADRA1BESR1PGR | |
| SCHEMBL10690885 | 0.81 | LMNA (0.52) | ADRA1DADRA1AADRA1BESR1PGR | |
| SCHEMBL10681421 | 0.81 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BESR1PGR | |
| SCHEMBL10688707 | 0.80 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BESR1PGR | |
| SCHEMBL18712848 | 0.79 | TRPM8 (0.55) | ACHEADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL10687988 | 0.79 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BESR1PGR | |
| SCHEMBL10682960 | 0.76 | DRD2 (0.48) | ADRA1DADRA1AADRA1BESR1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719208-A | 1,2,3,4,5,6-hexahydroazepino(4,5-B)indole derivatives, their preparation, intermediate compounds, and their application in therapeutics | OMNICHEM SOCIETE ANONYME (BE) | 1988-01-12 | — | — | US | disclosed |