Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.51 |
| ▸ | MMP12 | P39900 | 8/20 | 0.51 |
| ▸ | MMP13 | P45452 | 8/20 | 0.51 |
| ▸ | MMP14 | P50281 | 8/20 | 0.51 |
| ▸ | MMP9 | P14780 | 7/20 | 0.51 |
| ▸ | MMP1 | P03956 | 6/20 | 0.51 |
| ▸ | MMP3 | P08254 | 6/20 | 0.51 |
| ▸ | MMP8 | P22894 | 5/20 | 0.51 |
| ▸ | MMP16 | P51512 | 5/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044000 | 0.82 | MMP2 (0.40) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL11043794 | 0.80 | PKM (0.43) | MMP2MMP12MMP13MMP14MMP8 | |
| SCHEMBL8549823 | 0.78 | GABRA1 (0.32) | — | |
| SCHEMBL10646473 | 0.78 | GABRA1 (0.35) | — | |
| SCHEMBL6677573 | 0.76 | GAA (0.36) | — | |
| SCHEMBL1508334 | 0.75 | MMP2 (0.60) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL10690933 | 0.75 | GABRA1 (0.30) | — | |
| SCHEMBL10694395 | 0.75 | TDP1 (0.31) | TDP1 | |
| SCHEMBL9524237 | 0.75 | F2 (0.60) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL11049036 | 0.74 | CTSB (0.34) | MMP2MMP12MMP13MMP14MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485053-A | Process for the production of arylsulfonyl isocyanates | STAUFFER CHEMICAL COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| EP-0044209-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |