Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694507 | 0.85 | CNR1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2RIPK1LMNA | |
| SCHEMBL10694773 | 0.84 | MAPT (0.46) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8460589 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL10689506 | 0.78 | MMP8 (0.48) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10692612 | 0.77 | L3MBTL1 (0.47) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL10691473 | 0.77 | RIPK1 (0.53) | ALDH1A1SMN1; SMN2RIPK1PPIDHPGD | |
| SCHEMBL9501899 | 0.74 | MMP8 (0.50) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8463651 | 0.74 | TSHR (0.49) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL13387222 | 0.74 | TSHR (0.49) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL10692779 | 0.72 | POLB (0.61) | L3MBTL1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |