Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692273 | 0.85 | TSHR (0.43) | LMNAL3MBTL1SMN1; SMN2RIPK1ALDH1A1 | |
| SCHEMBL10691473 | 0.84 | RIPK1 (0.53) | LMNARAB9ASMN1; SMN2RIPK1ALDH1A1 | |
| SCHEMBL10692590 | 0.82 | ALDH1A1 (0.42) | LMNAHTTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9501899 | 0.82 | MMP8 (0.50) | CYP2C19NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10694465 | 0.80 | SMN1; SMN2 (0.54) | LMNAHTTL3MBTL1NPC1RAB9A | |
| SCHEMBL10692779 | 0.80 | POLB (0.61) | CNR1CYP2C19L3MBTL1NPC1RAB9A | |
| SCHEMBL10994453 | 0.80 | ACSS2 (0.41) | CNR1CNR2LMNAMTNR1AMTNR1B | |
| SCHEMBL10694310 | 0.79 | HDAC3 (0.43) | CNR1CNR2KCNN4CYP2C19HIF1A | |
| SCHEMBL10692252 | 0.79 | MEN1 (0.46) | CYP2C19LMNAHTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10694706 | 0.79 | POLB (0.56) | CYP2C19LMNAL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |