Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694465 | 0.92 | SMN1; SMN2 (0.54) | RIPK1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL10692204 | 0.90 | ALDH1A1 (0.49) | RIPK1LMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL10692252 | 0.90 | MEN1 (0.46) | RIPK1LMNASMN1; SMN2CYP2C9GAA | |
| SCHEMBL10693154 | 0.89 | NPC1 (0.54) | RAB9ACYP2C9ALDH1A1HPGD | |
| SCHEMBL9501899 | 0.85 | MMP8 (0.50) | MMP8RAB9AOPRK1SMN1; SMN2CYP2C9 | |
| SCHEMBL10694507 | 0.84 | CNR1 (0.40) | RIPK1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10692779 | 0.83 | POLB (0.61) | MMP8RAB9ASMN1; SMN2CYP2C9GAA | |
| SCHEMBL10694706 | 0.82 | POLB (0.56) | MMP8LMNASMN1; SMN2CYP2C9ALDH1A1 | |
| SCHEMBL10692590 | 0.79 | ALDH1A1 (0.42) | LMNARAB9ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL10994453 | 0.77 | ACSS2 (0.41) | LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |