Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702228 | 0.84 | MEN1 (0.55) | CA2PTPN11CA1MAPK1SMN1; SMN2 | |
| SCHEMBL9834718 | 0.83 | RORC (0.46) | CA2CA1MAPK1SMN1; SMN2HTT | |
| SCHEMBL10694255 | 0.79 | ALDH1A1 (0.59) | CA2PTPN11CA1MAPK1SMN1; SMN2 | |
| SCHEMBL10773767 | 0.76 | HTT (0.64) | CA2CA1HTTMEN1LMNA | |
| SCHEMBL10679045 | 0.74 | GAA (0.42) | CA2CA1LMNAALDH1A1 | |
| SCHEMBL10693087 | 0.74 | TDP1 (0.46) | MAPK1HTTALDH1A1 | |
| SCHEMBL7525890 | 0.70 | CA2 (0.68) | CA2PTPN11CA1MAPK1SMN1; SMN2 | |
| SCHEMBL9835822 | 0.69 | CYP2C9 (0.46) | CA2CA1MAPK1SMN1; SMN2HTT | |
| SCHEMBL7208755 | 0.69 | PTPN11 (0.61) | CA2PTPN11CA1MAPK1SMN1; SMN2 | |
| Risotilide SCHEMBL123045 | 0.68 | TRPV4 (0.49) | CA2CA1MAPK1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260901-A1 | Benzenesulphonamides useful as anti-arrythmic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-03-23 | — | — | EP | claimed |
| US-4721809-A | Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-26 | — | — | US | claimed |
| US-4721809-A | Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |