Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834718 | 0.85 | RORC (0.46) | CYP2C9ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL8864040 | 0.83 | CYP2C9 (0.44) | CYP2C9ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL10693088 | 0.80 | TDP1 (0.50) | TSHRMEN1KMT2ACA12CA1 | |
| Risotilide SCHEMBL123045 | 0.80 | TRPV4 (0.49) | CYP2C9ALDH1A1TSHRLMNAMEN1 | |
| Risotilide SCHEMBL635829 | 0.78 | LMNA (0.49) | CYP2C9ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL10780221 | 0.70 | GAA (0.43) | CYP2C9ALDH1A1TSHRLMNACA12 | |
| SCHEMBL10693476 | 0.69 | CA2 (0.49) | ALDH1A1LMNAMEN1KMT2ACA1 | |
| SCHEMBL10645045 | 0.68 | SMN1; SMN2 (0.57) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL10744418 | 0.67 | CA9 (0.49) | RORCCA12CA1CA2CA9 | |
| Bromide SCHEMBL10647145 | 0.67 | SMN1; SMN2 (0.56) | ALDH1A1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260901-B1 | BENZENESULPHONAMIDES USEFUL AS ANTI-ARRYTHMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-03-06 | — | — | EP | claimed |