Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696042 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL10698284 | 0.88 | MEN1 (0.39) | ALDH1A1KDM4EHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL10700273 | 0.88 | TNKS2 (0.43) | ALDH1A1KDM4ELMNAMAPTGPBAR1 | |
| SCHEMBL10698974 | 0.88 | KMT2A (0.37) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL10698603 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL10696613 | 0.87 | AURKA (0.40) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL10696397 | 0.86 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10MAPTTDP1 | |
| SCHEMBL10693698 | 0.85 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10698676 | 0.85 | KDM4E (0.35) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA | |
| SCHEMBL10700914 | 0.84 | HPGD (0.38) | ALDH1A1KDM4EHSD17B10L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |