Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008586 | 0.68 | L3MBTL1 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL8237320 | 0.62 | HTR2C (0.41) | — | |
| SCHEMBL13330639 | 0.62 | MMP2 (0.31) | — | |
| SCHEMBL3359002 | 0.61 | P2RX7 (0.46) | FDPSP2RX7 | |
| Methane SCHEMBL28929550 | 0.60 | POLB (0.31) | — | |
| Phosphoric Acid SCHEMBL28528859 | 0.60 | ALDH1A1 (0.50) | FDPSDAO | |
| SCHEMBL18572160 | 0.59 | CA12 (0.38) | CA12CA1CA2CA9 | |
| SCHEMBL2595451 | 0.59 | TDP1 (0.43) | FDPSCA2 | |
| Phosphoric Acid SCHEMBL27914386 | 0.59 | FDPS (0.47) | FDPSP2RX7CA2 | |
| SCHEMBL31520298 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273514-A1 | Novel bicyclic diphosphonate compounds and pharmaceutical compositions | Norwich Eaton Pharmaceuticals, Inc. (US) | 1988-07-06 | — | — | EP | disclosed |