Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GNG2 | P59768 | 1/20 | 0.31 |
| ▸ | GNB1 | P62873 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25569789 | 0.92 | MAPT (0.35) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL10692438 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4ERYR2MEN1 | |
| SCHEMBL10775826 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4ERYR2MEN1 | |
| SCHEMBL25569825 | 0.81 | MAPT (0.35) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL10693463 | 0.79 | ATM (0.42) | ALDH1A1GNG2GNB1MAPTKDM4E | |
| SCHEMBL4694745 | 0.77 | MAPT (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10691604 | 0.77 | HPGD (0.44) | ALDH1A1GNG2GNB1MAPTMEN1 | |
| SCHEMBL7098217 | 0.76 | ALDH1A1 (0.40) | SLC6A4ALDH1A1MAPTKDM4ERYR2 | |
| SCHEMBL10693207 | 0.76 | GNG2 (0.45) | ALDH1A1GNG2GNB1MAPT | |
| SCHEMBL6975541 | 0.76 | KDM4E (0.51) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791104-A | HYPOTENSIVE, ANTILIPEMIC, ANTIHROMBOTIC, ANTIHYPOXIC AGENTS | MAGGIONI-WINTHROP S.P.A. (IT) | 1988-12-13 | — | — | US | disclosed |
| WO-1987002359-A1 | DIHYDROBENZOTHIOPHENE AND THIOCHROMANE AMINOALCOHOLS | MAGGIONI-WINTHROP S.P.A. (IT) | 1987-04-23 | — | — | WO | disclosed |