Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692779 | 0.96 | POLB (0.61) | POLBMMP8KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9501899 | 0.91 | MMP8 (0.50) | POLBMMP8HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10693248 | 0.82 | TAAR1 (0.49) | KMT2AHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10691473 | 0.82 | RIPK1 (0.53) | MMP8HPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10693892 | 0.81 | SMN1; SMN2 (0.57) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10694507 | 0.79 | CNR1 (0.40) | KMT2AALDH1A1SMN1; SMN2LMNACYP2C19 | |
| SCHEMBL10694773 | 0.78 | MAPT (0.46) | POLBMMP8HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10689506 | 0.77 | MMP8 (0.48) | POLBMMP8HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL14497820 | 0.77 | POLB (0.90) | POLBMMP8KMT2AHPGDALDH1A1 | |
| SCHEMBL10993323 | 0.76 | ALDH1A1 (0.58) | POLBKMT2AHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |