Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FABP2 | P12104 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501899 | 0.91 | MMP8 (0.50) | TAAR1MAPTPLAAT5PLAAT4SMN1; SMN2 | |
| SCHEMBL10692252 | 0.87 | MEN1 (0.46) | LMNAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL10693892 | 0.86 | SMN1; SMN2 (0.57) | TAAR1MAPTPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10692779 | 0.83 | POLB (0.61) | TAAR1EPHX2CNR1SMN1; SMN2NPC1 | |
| SCHEMBL10694706 | 0.82 | POLB (0.56) | LMNASMN1; SMN2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL10993323 | 0.81 | ALDH1A1 (0.58) | MAPTLMNAPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10694773 | 0.79 | MAPT (0.46) | TAAR1MAPTPLAAT5PLAAT4LTA4H | |
| SCHEMBL10689506 | 0.78 | MMP8 (0.48) | TAAR1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10691473 | 0.77 | RIPK1 (0.53) | LMNASMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL10694507 | 0.77 | CNR1 (0.40) | LMNACNR1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |