Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CBFB | Q13951 | 4/20 | 0.33 |
| ▸ | METAP1 | P53582 | 3/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695258 | 0.90 | METAP2 (0.48) | METAP2CBFBMETAP1NPBWR1NPC1 | |
| SCHEMBL10575751 | 0.82 | METAP2 (0.34) | METAP2HDAC6 | |
| SCHEMBL10575162 | 0.81 | MTNR1A (0.37) | METAP2HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10580068 | 0.81 | METAP2 (0.60) | METAP2CBFBMETAP1NPC1LMNA | |
| SCHEMBL10576078 | 0.77 | HDAC6 (0.52) | HDAC6NPBWR1NPC1LMNARAB9A | |
| SCHEMBL31154200 | 0.76 | GAA (0.48) | METAP2NPC1LMNAPKMRAB9A | |
| SCHEMBL10577465 | 0.76 | NPBWR1 (0.53) | HDAC6NPBWR1NPC1PKMRAB9A | |
| SCHEMBL10573939 | 0.76 | KDM4E (0.49) | HDAC6NPBWR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10575172 | 0.76 | PDE2A (0.35) | METAP2HDAC6NPC1LMNARAB9A | |
| SCHEMBL10579325 | 0.75 | DGAT1 (0.51) | HDAC6NPBWR1SMN1; SMN2TRPV1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |