Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575178 | 0.92 | METAP2 (0.42) | ACACBKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL10575751 | 0.84 | METAP2 (0.34) | METAP2HDAC6 | |
| SCHEMBL10575172 | 0.82 | PDE2A (0.35) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL10695250 | 0.81 | METAP2 (0.38) | KDM4ESMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL10578748 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL10576178 | 0.80 | NPBWR1 (0.46) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL10574919 | 0.79 | MTNR1A (0.40) | MTNR1AMTNR1BACACBKDM4EALDH1A1 | |
| SCHEMBL10575761 | 0.76 | METAP2 (0.43) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL10695056 | 0.73 | AMY1A (0.41) | MTNR1AMTNR1BACACBTP53SMN1; SMN2 | |
| SCHEMBL10578223 | 0.72 | KDM4E (0.47) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |