Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700273 | 0.89 | TNKS2 (0.43) | KMT2ALMNAGAAMAPTTDP1 | |
| SCHEMBL10698037 | 0.88 | ALDH1A1 (0.38) | LMNASMN1; SMN2MAPTRECQLTDP1 | |
| SCHEMBL10698519 | 0.86 | CNR1 (0.41) | KMT2ALMNAOPRM1GAAMEN1 | |
| SCHEMBL10698241 | 0.83 | ADORA2B (0.34) | KMT2ATSHRLMNASMN1; SMN2GAA | |
| SCHEMBL10699950 | 0.83 | ADORA2B (0.33) | LMNASMN1; SMN2MAPTRECQLTDP1 | |
| SCHEMBL10698284 | 0.81 | MEN1 (0.39) | KMT2ATSHRLMNASMN1; SMN2GAA | |
| SCHEMBL10698470 | 0.81 | LMNA (0.32) | LMNASMN1; SMN2MAPTRECQLTDP1 | |
| SCHEMBL10700232 | 0.80 | TNKS2 (0.43) | KMT2ATSHRGAAMAPTTDP1 | |
| SCHEMBL10700914 | 0.79 | HPGD (0.38) | KMT2ATSHRLMNASMN1; SMN2GAA | |
| SCHEMBL10697413 | 0.78 | BMPR1B (0.39) | KMT2ATSHRLMNASMN1; SMN2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |