SCHEMBL1023973

SCHEMBL1023973

Nc1cc(C(F)(F)F)c(Cl)cc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
CA1 P00915 5/20 0.40
CA2 P00918 5/20 0.40
CA7 P43166 4/20 0.40
CA9 Q16790 4/20 0.40
CA12 O43570 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1025667 0.92 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10ALOX15ALOX12
SCHEMBL4851381 0.83 GAA (0.44) ALDH1A1HPGDHSD17B10ALOX15ALOX12
SCHEMBL440693 0.82 GAA (0.46) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL29770447 0.82 GAA (0.46) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL28737232 0.80 GAA (0.50) ALDH1A1MAPK1HTR3EHTR3BHTR3A
SCHEMBL23421386 0.79 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10ALOX15ALOX12
SCHEMBL29520987 0.78 GAA (0.45) ALDH1A1HPGDHSD17B10ALOX15ALOX12
SCHEMBL5038838 0.78 GAA (0.45) ALDH1A1HPGDHSD17B10ALOX15ALOX12
Hydrochloric Acid SCHEMBL7271091 0.78 GAA (0.48) ALDH1A1MAPK1HTR3EHTR3BHTR3A
SCHEMBL23421374 0.78 PGR (0.44) ALDH1A1HPGDHSD17B10ALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME CHECKMATE THERAPEUTICS INC. (KR) 2026-01-22 US disclosed
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
US-20250326777-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF HEPAITECH BEIJING BIOPHARMA TECH CO LTD (CN) 2025-10-23 US disclosed
EP-4605374-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF Hepaitech (Beijing) Biopharma Technology Co., Ltd. (CN) 2025-08-27 EP disclosed
US-12384769-B2 Heteroaryl-substituted aminoalkyl azole compounds as pesticides ELANCO ANIMAL HEALTH GMBH (DE) 2025-08-12 US disclosed
CN-120129676-A Compounds, compositions, and methods thereof 海湃泰克(北京)生物医药科技有限公司 2025-06-10 CN disclosed
CN-113939509-B Novel heteroaryl substituted aminoalkylazole compounds as pesticides 拜耳动物保健有限责任公司 2024-11-29 CN disclosed
WO-2024083210-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) 2024-04-25 WO disclosed
WO-2023229346-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME 주식회사 체크메이트테라퓨틱스 2023-11-30 WO disclosed
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO. LTD. (JP) 2023-02-16 US disclosed
US-20120108586-A1 ARTHROPOD PEST CONTROL METHOD AND COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-03 US disclosed
WO-2011049221-A1 COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-28 WO disclosed
WO-2011049222-A1 COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-28 WO disclosed
WO-2011049223-A1 COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-28 WO disclosed
WO-2011049220-A1 COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-28 WO disclosed
WO-2011040629-A1 COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-07 WO disclosed
CN-102006776-A Harmful arthropod control composition, and fused heterocyclic compound SUMITOMO CHEMICAL CO 2011-04-06 CN disclosed
US-20110039843-A1 HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-17 US disclosed
US-20110039843-A1 HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-17 US disclosed
EP-2274983-A1 HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108586-A1 ARTHROPOD PEST CONTROL METHOD AND COMPOSITION C5, C1S, C1R ALDH1A1 1245/4885HPGD 2199/4885HSD17B10 1028/4885
US-12384769-B2 Heteroaryl-substituted aminoalkyl azole compounds as pesticides DDT, CRY1, AAAS ALDH1A1 3552/4885HPGD 4643/4885HSD17B10 3096/4885
US-20110039843-A1 HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND C5, C9, C1S ALDH1A1 883/4885HPGD 2690/4885HSD17B10 1290/4885
US-20250326777-A1 COMPOUNDS, COMPOSITIONS AND METHODS THEREOF MRGPRX4, MRGPRX1, MRGPRX2 ALDH1A1 1047/4885HPGD 879/4885HSD17B10 2546/4885
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB ALDH1A1 287/4885HPGD 4260/4885HSD17B10 1662/4885
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF MYB, MLX, EP300 ALDH1A1 235/4885HPGD 4347/4885HSD17B10 1404/4885
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME NAMPT, NAPRT, NNT ALDH1A1 789/4885HPGD 320/4885HSD17B10 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.