Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | HINT1 | P49773 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ATG7 | O95352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.32 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708875 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HTTLMNAHSPA2 | |
| SCHEMBL10623372 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTHINT1LMNASMN1; SMN2 | |
| SCHEMBL10707759 | 0.68 | HINT1 (0.39) | ALDH1A1HINT1LMNATHRBSMN1; SMN2 | |
| SCHEMBL10623379 | 0.67 | LMNA (0.33) | ALDH1A1GALR3HINT1LMNATHRB | |
| SCHEMBL11181714 | 0.66 | FBP1 (0.47) | ALDH1A1LMNATHRBTSHRMAPT | |
| SCHEMBL9975391 | 0.65 | SLC15A1 (0.41) | ALDH1A1GALR3LMNATHRBSMN1; SMN2 | |
| SCHEMBL10620674 | 0.65 | ALDH1A1 (0.53) | ALDH1A1HTTHINT1LMNA | |
| SCHEMBL1625067 | 0.65 | SLC15A1 (0.41) | ALDH1A1GALR3LMNATHRBSMN1; SMN2 | |
| SCHEMBL8176532 | 0.65 | SLC15A1 (0.54) | ALDH1A1HINT1LMNATHRBSMN1; SMN2 | |
| SCHEMBL1624916 | 0.65 | SLC15A1 (0.47) | ALDH1A1HINT1LMNATHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155164-B1 | NOVEL CYANOIMIDAZOLE NUCLEOSIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-17 | — | — | EP | claimed |