Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713311 | 0.86 | GRIA1 (0.37) | ALDH1A1TNKS2PPARGKDM4EDDB1 | |
| SCHEMBL10713193 | 0.80 | CRHBP (0.44) | ALDH1A1PTGS2GSK3BPGR | |
| SCHEMBL10711646 | 0.78 | MEN1 (0.38) | ALDH1A1PGR | |
| SCHEMBL10712282 | 0.77 | BRD4 (0.36) | ALDH1A1BRD4PTGS2TNKS2PPARG | |
| SCHEMBL10711443 | 0.77 | PGR (0.49) | ALDH1A1BRD4PTGS2TNKS2PGR | |
| SCHEMBL11368672 | 0.75 | DAO (0.40) | ALDH1A1TNKS2GSK3BDDB1CRBN | |
| SCHEMBL10713932 | 0.75 | GABRA1 (0.39) | PTGS2TRPM2 | |
| SCHEMBL10714044 | 0.75 | TRPM2 (0.38) | PTGS2TRPM2GSK3BPGR | |
| SCHEMBL10713237 | 0.74 | MAOA (0.43) | ALDH1A1BRD4PTGS2TNKS2PGR | |
| SCHEMBL10711888 | 0.74 | BRD4 (0.40) | ALDH1A1BRD4PTGS2GSK3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |