Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.40 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286409 | 0.77 | LTA4H (0.47) | MMP1MMP13ANPEPERAP2MMP2 | |
| SCHEMBL7286416 | 0.77 | LTA4H (0.47) | MMP1MMP13ANPEPERAP2MMP2 | |
| SCHEMBL10715965 | 0.77 | ACE2 (0.53) | — | |
| SCHEMBL10718428 | 0.74 | REN (0.44) | ANPEPERAP2 | |
| SCHEMBL10717475 | 0.74 | REN (0.47) | NPC1RAB9ANPY5R | |
| SCHEMBL10716135 | 0.71 | MMP3 (0.51) | MMP1ANPEPERAP2MMP2MMP3 | |
| SCHEMBL5059759 | 0.70 | MMP1 (0.45) | MMP1MMP13ATMANPEPERAP2 | |
| SCHEMBL10715988 | 0.70 | REN (0.41) | MMP1MMP13ATM | |
| SCHEMBL10715825 | 0.68 | CPB2 (0.43) | EPHX2 | |
| SCHEMBL10716157 | 0.68 | CTSK (0.47) | MMP1MMP13HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |