Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716167 | 0.76 | CTSK (0.38) | KMT2ACACNA1BCTSL | |
| SCHEMBL10715988 | 0.74 | REN (0.41) | KMT2AATMMEN1CACNA1BREN | |
| SCHEMBL7274687 | 0.72 | REN (0.52) | RENCTSL | |
| SCHEMBL10718266 | 0.70 | CTSK (0.38) | KMT2ACACNA1BCTSL | |
| SCHEMBL10717336 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL8082012 | 0.67 | ATM (0.56) | KMT2AATMMEN1ACECTSL | |
| SCHEMBL7378383 | 0.67 | CTSL (0.48) | KMT2AATMCACNA1BACEREN | |
| SCHEMBL4357112 | 0.66 | HDAC4 (0.42) | KMT2ACACNA1B | |
| SCHEMBL10715943 | 0.66 | HDAC4 (0.42) | KMT2ACACNA1BREN | |
| SCHEMBL13605051 | 0.66 | HDAC4 (0.42) | KMT2ACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |