Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730881 | 0.84 | MAPT (0.54) | MAPTPKMALDH1A1HPGDCYP2C9 | |
| SCHEMBL10730781 | 0.78 | MAPT (0.58) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL10716583 | 0.77 | MAPT (0.56) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL10716377 | 0.77 | MAPT (0.56) | MAPTPKMALDH1A1KMT2AHPGD | |
| SCHEMBL10726196 | 0.76 | PKM (0.52) | MAPTPKMALDH1A1CYP2C9LMNA | |
| SCHEMBL10726719 | 0.76 | PKM (0.52) | MAPTPKMALDH1A1HPGDLMNA | |
| SCHEMBL10717754 | 0.76 | ALDH1A1 (0.52) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL10716620 | 0.76 | MAPT (0.46) | MAPTPKMALDH1A1KDM4EVNN1 | |
| SCHEMBL10730568 | 0.75 | PKM (0.51) | MAPTPKMALDH1A1GAAKDM4E | |
| SCHEMBL10726355 | 0.75 | MAPT (0.55) | MAPTPKMALDH1A1HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |