Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730881 | 0.81 | MAPT (0.54) | MAPTALDH1A1POLBKDM4EHPGD | |
| SCHEMBL10729369 | 0.81 | MAPT (0.45) | MAPTALDH1A1POLBKDM4EHPGD | |
| SCHEMBL10716446 | 0.78 | MAPT (0.50) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10732444 | 0.76 | MAPT (0.49) | MAPTALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL10719148 | 0.76 | MAPT (0.55) | MAPTALDH1A1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL10716583 | 0.75 | MAPT (0.56) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL10716377 | 0.75 | MAPT (0.56) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10730622 | 0.75 | MAPT (0.57) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10730384 | 0.74 | MAPT (0.56) | MAPTALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL24554275 | 0.74 | KDM4E (0.77) | MAPTALDH1A1POLBKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |