Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730622 | 0.90 | MAPT (0.57) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10728354 | 0.85 | MAPT (0.46) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10730881 | 0.84 | MAPT (0.54) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10716646 | 0.83 | MAPT (0.50) | MAPTPKMKDM4EKMT2ANPC1 | |
| SCHEMBL10716650 | 0.79 | MAPT (0.78) | MAPTPKMALDH1A1HPGDMEN1 | |
| SCHEMBL10719148 | 0.78 | MAPT (0.55) | MAPTPKMALDH1A1KDM4EMEN1 | |
| SCHEMBL10716446 | 0.77 | MAPT (0.50) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10716377 | 0.77 | MAPT (0.56) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10726196 | 0.76 | PKM (0.52) | MAPTPKMALDH1A1PTGS1LMNA | |
| SCHEMBL10717754 | 0.76 | ALDH1A1 (0.52) | MAPTPKMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |