Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716495 | 0.77 | GAA (0.46) | KDM4EGAAKMT2APKMLMNA | |
| SCHEMBL10717698 | 0.74 | MAPT (0.72) | ALDH1A1GAAMEN1KMT2APKM | |
| SCHEMBL10725846 | 0.69 | ALDH1A1 (0.54) | ALDH1A1GAAMEN1KMT2APKM | |
| SCHEMBL10726134 | 0.69 | MAPT (0.49) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10718981 | 0.68 | ALDH1A1 (0.43) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL10726650 | 0.68 | MEN1 (0.53) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4193666 | 0.66 | KDM4E (0.62) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL10730945 | 0.66 | PKM (0.58) | KDM4EALDH1A1MEN1KMT2APKM | |
| SCHEMBL28746777 | 0.65 | KDM4E (0.48) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL5779162 | 0.65 | KDM4E (0.49) | CASP3SENP8SENP7SENP6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |