Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 5/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719207 | 0.83 | KMT2A (0.45) | MEN1KMT2AOPRM1KDM4EPOLB | |
| SCHEMBL10494786 | 0.82 | OPRM1 (0.39) | MEN1KMT2AOPRM1OPRK1OPRL1 | |
| SCHEMBL10716492 | 0.77 | ADRB2 (0.56) | MEN1KMT2AKDM4EPOLBLMNA | |
| SCHEMBL10716608 | 0.74 | POLB (0.46) | KDM4EPOLBLMNAMAPK1ICMT | |
| SCHEMBL7753647 | 0.73 | OPRM1 (0.62) | MEN1KMT2AOPRM1OPRK1OPRL1 | |
| SCHEMBL10717752 | 0.73 | PLA2G4A (0.59) | — | |
| SCHEMBL10718886 | 0.73 | ICMT (0.45) | KDM4EPOLBLMNAMAPK1ICMT | |
| SCHEMBL21179535 | 0.70 | ADRB2 (0.40) | MEN1KMT2AOPRM1OPRK1OPRL1 | |
| SCHEMBL20769671 | 0.69 | KCNH2 (0.45) | MEN1KMT2AKDM4ELMNASCN5A | |
| SCHEMBL20769715 | 0.68 | AKR1C3 (0.46) | MEN1KMT2AKDM4ELMNACYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650810-A | OR INDOLE-5-THIOACETAMIDES | GLAXO GROUP LIMITED (GB) | 1987-03-17 | — | — | US | disclosed |