Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730384 | 0.77 | MAPT (0.56) | MAPTFDPSRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10716377 | 0.75 | MAPT (0.56) | MAPTRAB9APKMALDH1A1LMNA | |
| SCHEMBL969346 | 0.73 | FDPS (0.51) | MAPTFDPSCYP2A6F12PLAU | |
| SCHEMBL10730725 | 0.73 | MAPT (0.48) | MAPTRAB9APKMALDH1A1LMNA | |
| SCHEMBL10730881 | 0.73 | MAPT (0.54) | MAPTRAB9APKMALDH1A1LMNA | |
| SCHEMBL10716583 | 0.72 | MAPT (0.56) | MAPTRAB9APKMALDH1A1LMNA | |
| SCHEMBL28179274 | 0.71 | FDPS (0.50) | MAPTFDPSCYP2A6F12PLAU | |
| SCHEMBL10716650 | 0.71 | MAPT (0.78) | MAPTPKMALDH1A1LMNANPC1 | |
| SCHEMBL10730781 | 0.70 | MAPT (0.58) | MAPTNOS2RAB9APKMALDH1A1 | |
| SCHEMBL3062069 | 0.70 | FDPS (0.47) | MAPTFDPSCYP2A6F12PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |