Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730384 | 0.79 | MAPT (0.56) | MAPTALDH1A1KDM4EL3MBTL1NPC1 | |
| SCHEMBL10718982 | 0.73 | MAPT (0.48) | MAPTALDH1A1NPC1PKMLMNA | |
| SCHEMBL10814167 | 0.72 | MAPT (0.57) | MAPTALDH1A1L3MBTL1NPC1PKM | |
| SCHEMBL5439813 | 0.71 | HPGD (0.44) | MAPTALDH1A1KDM4ENPC1HTT | |
| SCHEMBL5439819 | 0.71 | HPGD (0.44) | MAPTALDH1A1KDM4ENPC1HTT | |
| SCHEMBL10725434 | 0.71 | MAPT (0.49) | MAPTALDH1A1KDM4EL3MBTL1NPC1 | |
| SCHEMBL10726355 | 0.70 | MAPT (0.55) | MAPTALDH1A1KDM4EL3MBTL1NPC1 | |
| SCHEMBL10730781 | 0.70 | MAPT (0.58) | MAPTALDH1A1KDM4ENPC1PKM | |
| SCHEMBL10730985 | 0.70 | MAPT (0.52) | MAPTALDH1A1L3MBTL1NPC1PKM | |
| SCHEMBL10716377 | 0.70 | MAPT (0.56) | MAPTALDH1A1KDM4ENPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |