Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725991 | 0.81 | PKM (0.46) | GRM5LMNAKDM4EMAPTPKM | |
| SCHEMBL10716578 | 0.80 | PKM (0.49) | GRM5MAPTPKM | |
| SCHEMBL10728346 | 0.78 | BAZ2B (0.48) | GRM5LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL10726379 | 0.78 | PKM (0.47) | HPGDKDM4EALDH1A1POLBMAPT | |
| SCHEMBL10727069 | 0.77 | ALDH1A1 (0.52) | HPGDLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL10726333 | 0.77 | PKM (0.48) | ALDH1A1POLBMAPTPKM | |
| SCHEMBL10731246 | 0.76 | PKM (0.45) | HPGDLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL10729011 | 0.75 | L3MBTL1 (0.50) | GRM5HPGDLMNAALDH1A1MAPT | |
| SCHEMBL10726113 | 0.74 | PKM (0.40) | LMNAALDH1A1MAPTPKM | |
| SCHEMBL10726196 | 0.74 | PKM (0.52) | LMNAALDH1A1POLBMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |