Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716578 | 0.76 | PKM (0.49) | PKMHCAR3MAPTHDAC3HDAC4 | |
| SCHEMBL10728346 | 0.74 | BAZ2B (0.48) | PKMHCAR3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10726379 | 0.74 | PKM (0.47) | PKMMAPTALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL10726100 | 0.74 | GRM5 (0.60) | PKMMAPTALDH1A1LMNA | |
| SCHEMBL10731246 | 0.74 | PKM (0.45) | PKMHCAR3MAPTALDH1A1LMNA | |
| SCHEMBL10727069 | 0.73 | ALDH1A1 (0.52) | PKMHCAR3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10726333 | 0.73 | PKM (0.48) | PKMHCAR3MAPTALDH1A1HDAC3 | |
| SCHEMBL10729011 | 0.71 | L3MBTL1 (0.50) | PKMHCAR3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10729039 | 0.70 | PKM (0.56) | PKMMAPTALDH1A1KMT2A | |
| SCHEMBL10726196 | 0.70 | PKM (0.52) | PKMMAPTALDH1A1SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |