Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716583 | 0.85 | MAPT (0.56) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10730622 | 0.79 | MAPT (0.57) | MAPTALDH1A1KDM4EHPGDHSD11B1 | |
| SCHEMBL10729369 | 0.76 | MAPT (0.45) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10859295 | 0.76 | BRD4 (0.43) | MAPTBRD4PKMALDH1A1KDM4E | |
| SCHEMBL10730881 | 0.74 | MAPT (0.54) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10716646 | 0.73 | MAPT (0.50) | MAPTPKMKDM4EHSD11B1SMN1; SMN2 | |
| SCHEMBL10716650 | 0.69 | MAPT (0.78) | MAPTPKMALDH1A1HPGD | |
| SCHEMBL10719148 | 0.68 | MAPT (0.55) | MAPTPKMALDH1A1KDM4EHSD11B1 | |
| SCHEMBL9390438 | 0.68 | BRD4 (0.49) | MAPTBRD4ALDH1A1FEN1 | |
| SCHEMBL10716446 | 0.68 | MAPT (0.50) | MAPTPKMALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |