Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730781 | 0.81 | MAPT (0.58) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10730881 | 0.78 | MAPT (0.54) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10728354 | 0.76 | MAPT (0.46) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10716446 | 0.75 | MAPT (0.50) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10716583 | 0.72 | MAPT (0.56) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10716377 | 0.72 | MAPT (0.56) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10726196 | 0.69 | PKM (0.52) | MAPTPKMALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10726134 | 0.69 | MAPT (0.49) | MAPTPKMALDH1A1KDM4EHPGD | |
| SCHEMBL10717754 | 0.69 | ALDH1A1 (0.52) | MAPTPKMALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10726719 | 0.69 | PKM (0.52) | MAPTPKMALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |