Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716583 | 0.76 | MAPT (0.56) | MAPTALDH1A1NPC1PKMKDM4E | |
| SCHEMBL10730622 | 0.76 | MAPT (0.57) | MAPTALDH1A1NPC1KDM4EL3MBTL1 | |
| SCHEMBL10730985 | 0.76 | MAPT (0.52) | MAPTALDH1A1NPC1PKMHTT | |
| SCHEMBL10716646 | 0.73 | MAPT (0.50) | MAPTNPC1PKMKDM4ERAB9A | |
| SCHEMBL10719148 | 0.71 | MAPT (0.55) | MAPTALDH1A1PKMKDM4EKMT2A | |
| SCHEMBL10730725 | 0.71 | MAPT (0.48) | MAPTALDH1A1NPC1PKMKDM4E | |
| SCHEMBL10731824 | 0.69 | PKM (0.49) | MAPTALDH1A1NPC1PKMKDM4E | |
| SCHEMBL10731823 | 0.69 | MAPT (0.59) | MAPTALDH1A1NPC1PKMKDM4E | |
| SCHEMBL10730568 | 0.69 | PKM (0.51) | MAPTALDH1A1PKMKDM4E | |
| SCHEMBL10730781 | 0.69 | MAPT (0.58) | MAPTALDH1A1NPC1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |