Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 9/20 | 0.45 |
| ▸ | MMP8 | P22894 | 9/20 | 0.45 |
| ▸ | MMP12 | P39900 | 9/20 | 0.45 |
| ▸ | MMP13 | P45452 | 9/20 | 0.45 |
| ▸ | MMP14 | P50281 | 9/20 | 0.45 |
| ▸ | MMP16 | P51512 | 9/20 | 0.45 |
| ▸ | MMP9 | P14780 | 8/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329810 | 0.80 | HSD11B1 (0.54) | HSD11B1POLBMAPTPKMABCC9 | |
| SCHEMBL8933453 | 0.79 | PKM (0.62) | HSD11B1PKMMMP2MMP8MMP12 | |
| SCHEMBL28305875 | 0.76 | ABCC9 (0.64) | HSD11B1POLBMAPTPKMABCC9 | |
| SCHEMBL10730924 | 0.76 | HTR6 (0.49) | MAPTPKMABCC9ABCC8KCNJ11 | |
| SCHEMBL11335297 | 0.76 | HSD11B1 (0.50) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6001994 | 0.75 | HTR6 (0.59) | HSD11B1PKMABCC9ABCC8KCNJ11 | |
| SCHEMBL28379517 | 0.75 | CA2 (0.58) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9460121 | 0.75 | HSD11B1 (0.59) | HSD11B1ELANEPOLBPKMABCC9 | |
| SCHEMBL8964467 | 0.75 | GAA (0.60) | HSD11B1MAPTABCC9ABCC8KCNJ11 | |
| SCHEMBL12336792 | 0.75 | HTR6 (0.58) | HSD11B1POLBMAPTABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656273-A | Process for producing sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |